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Repeat Sequences in Block 2 of Plasmodium falciparum Merozoite Surface Protein 1 Are Targets of Antibodies Associated with Protection from Malaria

Human antibodies to the block 2 region of Plasmodium falciparum merozoite surface protein 1 (MSP1) are associated with a reduced prospective risk of clinical malaria. Block 2 is highly polymorphic, but all known alleles can be grouped into three major types. Two of these types (the K1-like and MAD20...

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Bibliografiske detaljer
Main Authors: Polley, Spencer D., Tetteh, Kevin K. A., Cavanagh, David R., Pearce, Richard J., Lloyd, Jennifer M., Bojang, Kalifa A., Okenu, Daniel M. N., Greenwood, Brian M., McBride, Jana S., Conway, David J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC152097/
https://ncbi.nlm.nih.gov/pubmed/12654798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.4.1833-1842.2003
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