Repeat Sequences in Block 2 of Plasmodium falciparum Merozoite Surface Protein 1 Are Targets of Antibodies Associated with Protection from Malaria

Human antibodies to the block 2 region of Plasmodium falciparum merozoite surface protein 1 (MSP1) are associated with a reduced prospective risk of clinical malaria. Block 2 is highly polymorphic, but all known alleles can be grouped into three major types. Two of these types (the K1-like and MAD20...

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Detalhes bibliográficos
Main Authors: Polley, Spencer D., Tetteh, Kevin K. A., Cavanagh, David R., Pearce, Richard J., Lloyd, Jennifer M., Bojang, Kalifa A., Okenu, Daniel M. N., Greenwood, Brian M., McBride, Jana S., Conway, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Fungal and Parasitic Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC152097/
https://ncbi.nlm.nih.gov/pubmed/12654798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.4.1833-1842.2003
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