Repeat Sequences in Block 2 of Plasmodium falciparum Merozoite Surface Protein 1 Are Targets of Antibodies Associated with Protection from Malaria

Human antibodies to the block 2 region of Plasmodium falciparum merozoite surface protein 1 (MSP1) are associated with a reduced prospective risk of clinical malaria. Block 2 is highly polymorphic, but all known alleles can be grouped into three major types. Two of these types (the K1-like and MAD20...

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Bibliographic Details
Main Authors: Polley, Spencer D., Tetteh, Kevin K. A., Cavanagh, David R., Pearce, Richard J., Lloyd, Jennifer M., Bojang, Kalifa A., Okenu, Daniel M. N., Greenwood, Brian M., McBride, Jana S., Conway, David J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
Subjects:
Fungal and Parasitic Infections
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC152097/
https://ncbi.nlm.nih.gov/pubmed/12654798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.4.1833-1842.2003
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