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Repeat Sequences in Block 2 of Plasmodium falciparum Merozoite Surface Protein 1 Are Targets of Antibodies Associated with Protection from Malaria

Human antibodies to the block 2 region of Plasmodium falciparum merozoite surface protein 1 (MSP1) are associated with a reduced prospective risk of clinical malaria. Block 2 is highly polymorphic, but all known alleles can be grouped into three major types. Two of these types (the K1-like and MAD20...

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Autori principali: Polley, Spencer D., Tetteh, Kevin K. A., Cavanagh, David R., Pearce, Richard J., Lloyd, Jennifer M., Bojang, Kalifa A., Okenu, Daniel M. N., Greenwood, Brian M., McBride, Jana S., Conway, David J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC152097/
https://ncbi.nlm.nih.gov/pubmed/12654798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.4.1833-1842.2003
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