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Enhanced growth of tumors in SPARC null mice is associated with changes in the ECM
SPARC, a 32-kDa glycoprotein, participates in the regulation of morphogenesis and cellular differentiation through its modulation of cell-matrix interactions. Major functions defined for SPARC in vitro are de-adhesion and antiproliferation. In vivo, SPARC is restricted in its expression to remodelin...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Clinical Investigation
2003
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC151926/ https://ncbi.nlm.nih.gov/pubmed/12588887 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200316804 |
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