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Primary Mesenchymal Cells Isolated from SPARC-null Mice Exhibit Altered Morphology and Rates of Proliferation

SPARC (secreted protein acidic and rich in cysteine)/BM 40/osteonectin is a matricellular protein shown to function as a counteradhesive factor that induces cell rounding and as an inhibitor of cell proliferation. These activities have been defined in cell culture, in which interpretation has been c...

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Detalhes bibliográficos
Main Authors: Bradshaw, Amy D., Francki, Aleksandar, Motamed, Kouros, Howe, Chin, Sage, E. Helene
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC25344/
https://ncbi.nlm.nih.gov/pubmed/10233163
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