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Pten regulates collagen fibrillogenesis by fibroblasts through SPARC.

Collagen deposition contributes to both high mammographic density and breast cancer progression. Low stromal PTEN expression has been observed in as many as half of breast tumors and is associated with increases in collagen deposition, however the mechanism connecting PTEN loss to increased collagen...

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書誌詳細
主要な著者: Caitlin E Jones, Joe T Sharick, Sheila E Colbert, Vasudha C Shukla, Joshua M Zent, Michael C Ostrowski, Samir N Ghadiali, Steven T Sizemore, Jennifer L Leight
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science (PLoS) 2021-01-01
シリーズ:PLoS ONE
オンライン・アクセス:https://doi.org/10.1371/journal.pone.0245653
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