Chronic spinal cord compression associated with intervertebral disc degeneration in SPARC-null mice

Chronic spinal cord compression (CSCC) is induced by disc herniation and other reasons, leading to movement and sensation dysfunction, with a serious impact on quality of life. Spontaneous disc herniation rarely occurs in rodents, and therefore establishing a chronic spinal cord compression (CSCC) a...

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Autori principali:	Zhuo-Yao Li, Ai-Fang Zhou, Gan Li, Long-Yun Zhou, Pei-Min Pu, Ke Zhu, Zhong Zheng, Yong-Jun Wang, Qian-Qian Liang, Min Yao, Xue-Jun Cui
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Wolters Kluwer Medknow Publications 2023-01-01
Serie:	Neural Regeneration Research
Soggetti:	apoptosis; astrocytes; chronic spinal cord compression; disc degeneration; disc herniation; macrophages; microglia; neuroinflammation; neurons; nod-like receptor protein 3 inflammasomes; secreted protein acidic and rich in cysteine
Accesso online:	http://www.nrronline.org/article.asp?issn=1673-5374;year=2023;volume=18;issue=3;spage=634;epage=642;aulast=Li
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