c-Fms and the α(v)β(3) integrin collaborate during osteoclast differentiation
β(3) integrin–null osteoclasts are dysfunctional, but their numbers are increased in vivo. In vitro, however, the number of β(3)(–/–) osteoclasts is reduced because of arrested differentiation. This paradox suggests cytokine regulation of β(3)(–/–) osteoclastogenesis differs in vitro and in vivo. In...
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| Udgivet i: | J Clin Invest |
|---|---|
| Principais autores: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151897/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12618529/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI16924 |
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