A genetic analysis of integrin function: Glanzmann thrombasthenia in vitro

Glanzmann thrombasthenia, an inherited bleeding disorder, can be caused by a defect or deficiency in platelet integrin α(IIb)β(3) (GPIIb-IIIa). Studies of thrombasthenia variants have facilitated identification of sites involved in the functions of α(IIb)β(3) and other integrins. Such sites include...

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Bibliographic Details
Main Authors: Baker, Elizabeth K., Tozer, Eileen Collins, Pfaff, Martin, Shattil, Sanford J., Loftus, Joseph C., Ginsberg, Mark H.
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences of the USA 1997
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC20027/
https://ncbi.nlm.nih.gov/pubmed/9050889
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