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Glanzmann thrombasthenia
Glanzmann thrombasthenia (GT) is a rare autosomal recessive bleeding syndrome affecting the megakaryocyte lineage and characterized by lack of platelet aggregation. The molecular basis is linked to quantitative and/or qualitative abnormalities of αIIbβ3 integrin. This receptor mediates the binding o...
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| Format: | Artigo |
| Jezik: | Inglês |
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BioMed Central
2006
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| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1475837/ https://ncbi.nlm.nih.gov/pubmed/16722529 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1172-1-10 |
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