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c-Fms and the α(v)β(3) integrin collaborate during osteoclast differentiation

β(3) integrin–null osteoclasts are dysfunctional, but their numbers are increased in vivo. In vitro, however, the number of β(3)(–/–) osteoclasts is reduced because of arrested differentiation. This paradox suggests cytokine regulation of β(3)(–/–) osteoclastogenesis differs in vitro and in vivo. In...

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Bibliografske podrobnosti
Main Authors: Faccio, Roberta, Takeshita, Sunao, Zallone, Alberta, Ross, F. Patrick, Teitelbaum, Steven L.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2003
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC151897/
https://ncbi.nlm.nih.gov/pubmed/12618529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200316924
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