NIK stabilization in osteoclasts results in osteoporosis and enhanced inflammatory osteolysis.

<h4>Background</h4>Maintenance of healthy bone requires the balanced activities of osteoclasts (OCs), which resorb bone, and osteoblasts, which build bone. Disproportionate action of OCs is responsible for the bone loss associated with postmenopausal osteoporosis and rheumatoid arthritis. NF-κB indu...

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書誌詳細

主要な著者:	Chang Yang, Kathleen McCoy, Jennifer L Davis, Marc Schmidt-Supprian, Yoshiteru Sasaki, Roberta Faccio, Deborah Veis Novack
フォーマット:	Artigo
言語:	Inglês
出版事項:	Public Library of Science (PLoS) 2010-11-01
シリーズ:	PLoS ONE
オンライン･アクセス:	https://doi.org/10.1371/journal.pone.0015383
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