Increased ABCA1 activity protects against atherosclerosis

The ABC transporter ABCA1 plays a key role in the first steps of the reverse cholesterol transport pathway by mediating lipid efflux from macrophages. Previously, it was demonstrated that human ABCA1 overexpression in vivo in transgenic mice results in a mild elevation of plasma HDL levels and incre...

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Autores principales: Singaraja, Roshni R., Fievet, Catherine, Castro, Graciela, James, Erick R., Hennuyer, Nathalie, Clee, Susanne M., Bissada, Nagat, Choy, Jonathan C., Fruchart, Jean-Charles, McManus, Bruce M., Staels, Bart, Hayden, Michael R.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2002
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC151034/
https://ncbi.nlm.nih.gov/pubmed/12093886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI15748
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