Absence of stearoyl-CoA desaturase-1 ameliorates features of the metabolic syndrome in LDLR-deficient mice

A combination of the interrelated metabolic risk factors obesity, insulin resistance, dyslipidemia, and hypertension, often described as the “metabolic syndrome,” is known to increase the risk of developing cardiovascular disease and diabetes. Stearoyl-coenzyme A desaturase (SCD) activity has been i...

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Vydáno v:J Lipid Res
Hlavní autoři: MacDonald, Marcia L. E., Singaraja, Roshni R., Bissada, Nagat, Ruddle, Piers, Watts, Russell, Karasinska, Joanna M., Gibson, William T., Fievet, Catherine, Vance, Jean E., Staels, Bart, Hayden, Michael R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5017869/
https://ncbi.nlm.nih.gov/pubmed/17960025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M700478-JLR200
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