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Absence of stearoyl-CoA desaturase-1 ameliorates features of the metabolic syndrome in LDLR-deficient mice

A combination of the interrelated metabolic risk factors obesity, insulin resistance, dyslipidemia, and hypertension, often described as the “metabolic syndrome,” is known to increase the risk of developing cardiovascular disease and diabetes. Stearoyl-coenzyme A desaturase (SCD) activity has been i...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: MacDonald, Marcia L. E., Singaraja, Roshni R., Bissada, Nagat, Ruddle, Piers, Watts, Russell, Karasinska, Joanna M., Gibson, William T., Fievet, Catherine, Vance, Jean E., Staels, Bart, Hayden, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5017869/
https://ncbi.nlm.nih.gov/pubmed/17960025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M700478-JLR200
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