Despite antiatherogenic metabolic characteristics, SCD1-deficient mice have increased inflammation and atherosclerosis

OBJECTIVE: Absence of stearoyl-CoA desaturase-1 (SCD1) in mice reduces plasma triglycerides and provides protection from obesity and insulin resistance, which would be predicted to be associated with reduced susceptibility to atherosclerosis. The aim of this study was to determine the effect of SCD1...

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Autors principals: MacDonald, Marcia L.E., van Eck, Miranda, Hildebrand, Reeni B., Wong, Brian W. C., Bissada, Nagat, Ruddle, Piers, Kontush, Anatol, Hussein, Hala, Pouladi, Mahmoud A., Chapman, M. John, Fievet, Catherine, van Berkel, Theo J.C., Staels, Bart, McManus, Bruce M., Hayden, Michael R.
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2873333/
https://ncbi.nlm.nih.gov/pubmed/19095997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.108.181099
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