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Leukocyte ABCA1 Remains Atheroprotective in Splenectomized LDL Receptor Knockout Mice
AIM: ATP-binding cassette transporter A1 (ABCA1) is an important mediator of macrophage cholesterol efflux. It mediates the efflux of cellular cholesterol to lipid-poor apolipoprotein A-I. LDL receptor (LDLr) knockout (KO) mice deficient for leukocyte ABCA1 (ABCA1 KO→LDLr KO) show increased atherosc...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3485037/ https://ncbi.nlm.nih.gov/pubmed/23133551 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048080 |
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