Intestinal ABCA1 directly contributes to HDL biogenesis in vivo

Plasma HDL cholesterol levels are inversely related to risk for atherosclerosis. The ATP-binding cassette, subfamily A, member 1 (ABCA1) mediates the rate-controlling step in HDL particle formation, the assembly of free cholesterol and phospholipids with apoA-I. ABCA1 is expressed in many tissues; h...

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Hlavní autoři: Brunham, Liam R., Kruit, Janine K., Iqbal, Jahangir, Fievet, Catherine, Timmins, Jenelle M., Pape, Terry D., Coburn, Bryan A., Bissada, Nagat, Staels, Bart, Groen, Albert K., Hussain, M. Mahmood, Parks, John S., Kuipers, Folkert, Hayden, Michael R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2006
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1401485/
https://ncbi.nlm.nih.gov/pubmed/16543947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI27352
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