Intestinal ABCA1 directly contributes to HDL biogenesis in vivo

Plasma HDL cholesterol levels are inversely related to risk for atherosclerosis. The ATP-binding cassette, subfamily A, member 1 (ABCA1) mediates the rate-controlling step in HDL particle formation, the assembly of free cholesterol and phospholipids with apoA-I. ABCA1 is expressed in many tissues; h...

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Detalhes bibliográficos
Main Authors: Brunham, Liam R., Kruit, Janine K., Iqbal, Jahangir, Fievet, Catherine, Timmins, Jenelle M., Pape, Terry D., Coburn, Bryan A., Bissada, Nagat, Staels, Bart, Groen, Albert K., Hussain, M. Mahmood, Parks, John S., Kuipers, Folkert, Hayden, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2006
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1401485/
https://ncbi.nlm.nih.gov/pubmed/16543947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI27352
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