HDL and pancreatic β cells: a SMO-king gun?(1)

por Brunham, Liam R.
Publicado no J Lipid Res (2020)

Regulated cell death pathways in doxorubicin-induced cardiotoxicity

por Christidi, Effimia, Brunham, Liam R.
Publicado no Cell Death Dis (2021)

Hunting human disease genes: lessons from the past, challenges for the future

por Brunham, Liam R., Hayden, Michael R.
Publicado em 2013

Association of Monogenic vs Polygenic Hypercholesterolemia With Risk of Atherosclerotic Cardiovascular Disease

por Trinder, Mark, Francis, Gordon A., Brunham, Liam R.
Publicado no JAMA Cardiol (2020)

Causal Inference for Genetically Determined Levels of High-Density Lipoprotein Cholesterol and Risk of Infectious Disease

por Trinder, Mark, Walley, Keith R., Boyd, John H., Brunham, Liam R.
Publicado no Arterioscler Thromb Vasc Biol (2020)

Patient Perspectives Regarding Genetic Testing for Familial Hypercholesterolemia

por Marchand, Miles, Chen, Victoria, Trinder, Mark, Cermakova, Lubomira, Brunham, Liam R.
Publicado no CJC Open (2021)

Cholesterol in islet dysfunction and type 2 diabetes

por Brunham, Liam R., Kruit, Janine K., Verchere, C. Bruce, Hayden, Michael R.
Publicado em 2008

Role of genetics in the prediction of statin-associated muscle symptoms and optimization of statin use and adherence

por Brunham, Liam R, Baker, Steven, Mammen, Andrew, Mancini, G B John, Rosenson, Robert S
Publicado no Cardiovasc Res (2018)

Accurate Prediction of the Functional Significance of Single Nucleotide Polymorphisms and Mutations in the ABCA1 Gene

por Brunham, Liam R, Singaraja, Roshni R, Pape, Terry D, Kejariwal, Anish, Thomas, Paul D, Hayden, Michael R
Publicado em 2005

Polygenic Contribution to Low-Density Lipoprotein Cholesterol Levels and Cardiovascular Risk in Monogenic Familial Hypercholesterolemia

por Trinder, Mark, Paquette, Martine, Cermakova, Lubomira, Ban, Matthew R., Hegele, Robert A., Baass, Alexis, Brunham, Liam R.
Publicado no Circ Genom Precis Med (2020)

Premature Atherosclerotic Cardiovascular Disease: Trends in Incidence, Risk Factors, and Sex‐Related Differences, 2000 to 2016

por Vikulova, Diana N., Grubisic, Maja, Zhao, Yinshan, Lynch, Kelsey, Humphries, Karin H., Pimstone, Simon N., Brunham, Liam R.
Publicado no J Am Heart Assoc (2019)

Priorities for Services in Young Patients With Atherosclerotic Cardiovascular Disease and Their Family Members: An Exploratory Mixed-Methods Study

por Cho, Raymond Y., Weng, Jian, Lynch, Kelsey, Ng, Phoebe, Brown, Chad, Hoens, Alison M., Barry, Kevin, Brunham, Liam R., Pimstone, Simon
Publicado no CJC Open (2019)

Prevalence and characteristics of adverse drug reactions at admission to hospital: a prospective observational study

por Chan, Sze Ling, Ang, Xiaohui, Sani, Levana L., Ng, Hong Yen, Winther, Michael D., Liu, Jian Jun, Brunham, Liam R., Chan, Alexandre
Publicado no Br J Clin Pharmacol (2016)

Variation in RARG increases susceptibility to doxorubicin-induced cardiotoxicity in patient specific induced pluripotent stem cell-derived cardiomyocytes

por Christidi, Effimia, Huang, Haojun, Shafaattalab, Sanam, Maillet, Agnes, Lin, Eric, Huang, Kate, Laksman, Zachary, Davis, Margot K., Tibbits, Glen F., Brunham, Liam R.
Publicado no Sci Rep (2020)

Carriers of Loss-of-Function Mutations in ABCA1 Display Pancreatic β-Cell Dysfunction

por Vergeer, Menno, Brunham, Liam R., Koetsveld, Joris, Kruit, Janine K., Verchere, C. Bruce, Kastelein, John J.P., Hayden, Michael R., Stroes, Erik S.G.
Publicado em 2010

Modeling Doxorubicin-Induced Cardiotoxicity in Human Pluripotent Stem Cell Derived-Cardiomyocytes

por Maillet, Agnes, Tan, Kim, Chai, Xiaoran, Sadananda, Singh N., Mehta, Ashish, Ooi, Jolene, Hayden, Michael R., Pouladi, Mahmoud A., Ghosh, Sujoy, Shim, Winston, Brunham, Liam R.
Publicado no Sci Rep (2016)

Association and clinical utility of NAT2 in the prediction of isoniazid-induced liver injury in Singaporean patients

por Chan, Sze Ling, Chua, Angeline Poh Gek, Aminkeng, Folefac, Chee, Cynthia Bin Eng, Jin, Shengnan, Loh, Marie, Gan, Suay Hong, Wang, Yee Tang, Brunham, Liam R.
Publicado no PLoS One (2017)

Genetic diversity of variants involved in drug response and metabolism in Sri Lankan populations: implications for clinical implementation of pharmacogenomics

por Chan, Sze Ling, Samaranayake, Nilakshi, Ross, Colin J.D., Toh, Meng Tiak, Carleton, Bruce, Hayden, Michael R., Teo, Yik Ying, Dissanayake, Vajira H.W., Brunham, Liam R.
Publicado no Pharmacogenet Genomics (2016)

Lipid-lowering therapy for primary prevention of premature atherosclerotic coronary artery disease: Eligibility, utilization, target achievement, and predictors of initiation

por Vikulova, Diana N., Skorniakov, Ilia S., Bitoiu, Brendon, Brown, Chad, Theberge, Emilie, Fordyce, Christopher B., Francis, Gordon A., Humphries, Karin H., Mancini, G.B. John, Pimstone, Simon N., Brunham, Liam R.
Publicado no Am J Prev Cardiol (2020)

CETP genetic variant rs1800777 (allele A) is associated with abnormally low HDL-C levels and increased risk of AKI during sepsis

por Genga, Kelly Roveran, Trinder, Mark, Kong, HyeJin Julia, Li, Xuan, Leung, Alex K. K., Shimada, Tadanaga, Walley, Keith R., Russell, James A., Francis, Gordon A., Brunham, Liam R., Boyd, John H.
Publicado no Sci Rep (2018)