Polygenic Contribution to Low-Density Lipoprotein Cholesterol Levels and Cardiovascular Risk in Monogenic Familial Hypercholesterolemia

Familial hypercholesterolemia (FH) is a common autosomal codominant genetic disorder, which causes elevated levels of low-density lipoprotein cholesterol (LDL-C) and increased risk of premature atherosclerotic cardiovascular disease (ASCVD). Even among individuals with monogenic FH, there is substan...

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Dettagli Bibliografici
Pubblicato in:Circ Genom Precis Med
Autori principali: Trinder, Mark, Paquette, Martine, Cermakova, Lubomira, Ban, Matthew R., Hegele, Robert A., Baass, Alexis, Brunham, Liam R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Lippincott Williams & Wilkins 2020
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7889287/
https://ncbi.nlm.nih.gov/pubmed/33079599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGEN.120.002919
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