Carriers of Loss-of-Function Mutations in ABCA1 Display Pancreatic β-Cell Dysfunction

OBJECTIVE: Abnormal cellular cholesterol handling in islets may contribute to β-cell dysfunction in type 2 diabetes. β-Cell deficiency for the ATP binding cassette transporter A1 (ABCA1), which mediates the efflux of cellular cholesterol, leads to altered intracellular cholesterol homeostasis and im...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Vergeer, Menno, Brunham, Liam R., Koetsveld, Joris, Kruit, Janine K., Verchere, C. Bruce, Kastelein, John J.P., Hayden, Michael R., Stroes, Erik S.G.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Diabetes Association 2010
Gaiak:
Original Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2845043/
https://ncbi.nlm.nih.gov/pubmed/20067955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc09-1562
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak