Specific Loss of Brain ABCA1 Increases Brain Cholesterol Uptake and Influences Neuronal Structure and Function

The expression of the cholesterol transporter ATP-binding cassette transporter A1 (ABCA1) in the brain and its role in the lipidation of apolipoproteins indicate that ABCA1 may play a critical role in brain cholesterol metabolism. To investigate the role of ABCA1 in brain cholesterol homeostasis and...

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Detalhes bibliográficos
Main Authors: Karasinska, Joanna M., Rinninger, Franz, Lütjohann, Dieter, Ruddle, Piers, Franciosi, Sonia, Kruit, Janine K., Singaraja, Roshni R., Hirsch-Reinshagen, Veronica, Fan, Jianjia, Brunham, Liam R., Bissada, Nagat, Ramakrishnan, Rajasekhar, Wellington, Cheryl L., Parks, John S., Hayden, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2009
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2678874/
https://ncbi.nlm.nih.gov/pubmed/19295162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4741-08.2009
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