Intestinal ABCA1 directly contributes to HDL biogenesis in vivo

Plasma HDL cholesterol levels are inversely related to risk for atherosclerosis. The ATP-binding cassette, subfamily A, member 1 (ABCA1) mediates the rate-controlling step in HDL particle formation, the assembly of free cholesterol and phospholipids with apoA-I. ABCA1 is expressed in many tissues; h...

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Autors principals: Brunham, Liam R., Kruit, Janine K., Iqbal, Jahangir, Fievet, Catherine, Timmins, Jenelle M., Pape, Terry D., Coburn, Bryan A., Bissada, Nagat, Staels, Bart, Groen, Albert K., Hussain, M. Mahmood, Parks, John S., Kuipers, Folkert, Hayden, Michael R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2006
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1401485/
https://ncbi.nlm.nih.gov/pubmed/16543947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI27352
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