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Hepatobiliary cholesterol transport is not impaired in Abca1-null mice lacking HDL

The ABC transporter ABCA1 regulates HDL levels and is considered to control the first step of reverse cholesterol transport from the periphery to the liver. To test this concept, we studied the effect of ABCA1 deficiency on hepatic metabolism and hepatobiliary flux of cholesterol in mice. Hepatic li...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Groen, Albert K., Bloks, Vincent W., Bandsma, Robert H.J., Ottenhoff, Roelof, Chimini, Giovanna, Kuipers, Folkert
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2001
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC200929/
https://ncbi.nlm.nih.gov/pubmed/11560953
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