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Origins of intestinal ABCA1-mediated HDL-cholesterol

The origins of cholesterol utilized by intestinal ABCA1 were investigated in the human intestinal cell line Caco-2. Influx of apical membrane cholesterol increases ABCA1 mRNA and mass, resulting in enhanced efflux of HDL-cholesterol. Luminal (micellar) cholesterol and newly synthesized cholesterol a...

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Autori principali: Field, F. Jeffrey, Watt, Kim, Mathur, Satya N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582371/
https://ncbi.nlm.nih.gov/pubmed/18711208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M800302-JLR200
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