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TNF-α decreases ABCA1 expression and attenuates HDL cholesterol efflux in the human intestinal cell line Caco-2
HDL cholesterol levels are decreased in Crohn's disease, a tumor necrosis factor-α (TNF-α)–driven chronic inflammatory condition involving the gastrointestinal tract. ATP-binding cassette transporter A1 (ABCA1), one of several liver X receptor (LXR) target genes, is a cell surface transporter t...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The American Society for Biochemistry and Molecular Biology
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3035503/ https://ncbi.nlm.nih.gov/pubmed/20103810 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M002410 |
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