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Hepatobiliary cholesterol transport is not impaired in Abca1-null mice lacking HDL

The ABC transporter ABCA1 regulates HDL levels and is considered to control the first step of reverse cholesterol transport from the periphery to the liver. To test this concept, we studied the effect of ABCA1 deficiency on hepatic metabolism and hepatobiliary flux of cholesterol in mice. Hepatic li...

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Détails bibliographiques
Auteurs principaux: Groen, Albert K., Bloks, Vincent W., Bandsma, Robert H.J., Ottenhoff, Roelof, Chimini, Giovanna, Kuipers, Folkert
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2001
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC200929/
https://ncbi.nlm.nih.gov/pubmed/11560953
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