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Mechanisms by which IκB proteins control NF-κB activity

The biological activity of the transcription factor NF-κB is differentially controlled by three IκB proteins, IκBα, IκBβ, and IκBɛ. We have examined the molecular basis for the differential inhibitory strengths of IκB proteins by constructing hybrid IκBs and found that the first ankyrin repeat of Iκ...

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Bibliographische Detailangaben
Hauptverfasser: Simeonidis, Simos, Stauber, Deborah, Chen, Guoying, Hendrickson, Wayne A., Thanos, Dimitris
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 1999
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC15091/
https://ncbi.nlm.nih.gov/pubmed/9874770
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