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Mechanisms by which IκB proteins control NF-κB activity

The biological activity of the transcription factor NF-κB is differentially controlled by three IκB proteins, IκBα, IκBβ, and IκBɛ. We have examined the molecular basis for the differential inhibitory strengths of IκB proteins by constructing hybrid IκBs and found that the first ankyrin repeat of Iκ...

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Bibliografske podrobnosti
Main Authors: Simeonidis, Simos, Stauber, Deborah, Chen, Guoying, Hendrickson, Wayne A., Thanos, Dimitris
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 1999
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC15091/
https://ncbi.nlm.nih.gov/pubmed/9874770
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