Regulation of the NK-1 receptor gene expression in human macrophage cells via an NF-κB site on its promoter

We report here that human monocytic/macrophage THP-1 cells express the neurokinin 1 receptor (NK-1R), and that exposure of these cells to the proinflammatory cytokine IL-1β increased the expression of the NK-1R gene at the mRNA and protein levels. Because IL-1β function involves nuclear factor κB (N...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Simeonidis, Simos, Castagliuolo, Ignazio, Pan, Amy, Liu, Jennifer, Wang, Chi-Chi, Mykoniatis, Andreas, Pasha, Asia, Valenick, Leyla, Sougioultzis, Stavros, Zhao, Dezheng, Pothoulakis, Charalabos
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2003
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC151448/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12594338/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0530112100
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