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Regulation of the NK-1 receptor gene expression in human macrophage cells via an NF-κB site on its promoter
We report here that human monocytic/macrophage THP-1 cells express the neurokinin 1 receptor (NK-1R), and that exposure of these cells to the proinflammatory cytokine IL-1β increased the expression of the NK-1R gene at the mRNA and protein levels. Because IL-1β function involves nuclear factor κB (N...
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| Autors principals: | , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The National Academy of Sciences
2003
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC151448/ https://ncbi.nlm.nih.gov/pubmed/12594338 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0530112100 |
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