Mechanisms by which IκB proteins control NF-κB activity
The biological activity of the transcription factor NF-κB is differentially controlled by three IκB proteins, IκBα, IκBβ, and IκBɛ. We have examined the molecular basis for the differential inhibitory strengths of IκB proteins by constructing hybrid IκBs and found that the first ankyrin repeat of Iκ...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1999
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15091/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9874770/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.1.49 |
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