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Mechanisms by which IκB proteins control NF-κB activity

The biological activity of the transcription factor NF-κB is differentially controlled by three IκB proteins, IκBα, IκBβ, and IκBɛ. We have examined the molecular basis for the differential inhibitory strengths of IκB proteins by constructing hybrid IκBs and found that the first ankyrin repeat of Iκ...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Simeonidis, Simos, Stauber, Deborah, Chen, Guoying, Hendrickson, Wayne A., Thanos, Dimitris
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1999
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15091/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9874770/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.1.49
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