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Mechanisms by which IκB proteins control NF-κB activity

The biological activity of the transcription factor NF-κB is differentially controlled by three IκB proteins, IκBα, IκBβ, and IκBɛ. We have examined the molecular basis for the differential inhibitory strengths of IκB proteins by constructing hybrid IκBs and found that the first ankyrin repeat of Iκ...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Simeonidis, Simos, Stauber, Deborah, Chen, Guoying, Hendrickson, Wayne A., Thanos, Dimitris
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15091/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9874770/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.1.49
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