Disruption of Imprinted Genes at Chromosome Region 11p15.5 in Paediatric Rhabdomyosarcoma

Rhabdomyosarcomas are characterized by loss of heterozygosity (LOH) at chromosome region 11p15.5, a region known to contain several imprinted genes including insulin-like growth factor 2 (IGF2), H19, and p57(KIP2). We analyzed 48 primary tumour samples and found distinct genetic changes at 11p15.5 i...

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Detaylı Bibliyografya
Asıl Yazarlar: Anderson, John, Gordon, Anthony, McManus, Aidan, Shipley, Janet, Pritchard-Jones, Kathy
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Stockton Press 1999
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1508094/
https://ncbi.nlm.nih.gov/pubmed/10935489
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