Detection of the PAX3-FKHR fusion gene in paediatric rhabdomyosarcoma: a reproducible predictor of outcome?

Rhabdomyosarcoma has 2 major histological subtypes, embryonal and alveolar. Alveolar histology is associated with the fusion genes PAX3-FKHR and PAX7-FKHR. Definition of alveolar has been complicated by changes in terminology and subjectivity. It is currently unclear whether adverse clinical behavio...

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Bibliografske podrobnosti
Main Authors: Anderson, J, Gordon, T, McManus, A, Mapp, T, Gould, S, Kelsey, A, McDowell, H, Pinkerton, R, Shipley, J, Pritchard-Jones, K
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2001
Teme:
Regular Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2375077/
https://ncbi.nlm.nih.gov/pubmed/11556833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2001.2008
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