Disruption of Imprinted Genes at Chromosome Region 11p15.5 in Paediatric Rhabdomyosarcoma

Rhabdomyosarcomas are characterized by loss of heterozygosity (LOH) at chromosome region 11p15.5, a region known to contain several imprinted genes including insulin-like growth factor 2 (IGF2), H19, and p57(KIP2). We analyzed 48 primary tumour samples and found distinct genetic changes at 11p15.5 i...

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Detalhes bibliográficos
Main Authors: Anderson, John, Gordon, Anthony, McManus, Aidan, Shipley, Janet, Pritchard-Jones, Kathy
Formato: Artigo
Idioma:Inglês
Publicado em: Stockton Press 1999
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1508094/
https://ncbi.nlm.nih.gov/pubmed/10935489
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