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Novel familial distal imprinting centre 1 (11p15.5) deletion provides further insights in imprinting regulation

BACKGROUND: Deletions of the imprinting centre 1 (IC1) in 11p15.5 are rare and their clinical significance is not only influenced by their parental origin but also by their exact genomic localization. In case the maternal IC1 allele is affected, the deletion is associated with the overgrowth disorde...

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Опубликовано в: :Clin Epigenetics
Главные авторы: Kraft, Florian, Wesseler, Katharina, Begemann, Matthias, Kurth, Ingo, Elbracht, Miriam, Eggermann, Thomas
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6377752/
https://ncbi.nlm.nih.gov/pubmed/30770769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-019-0629-x
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