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Novel familial distal imprinting centre 1 (11p15.5) deletion provides further insights in imprinting regulation

BACKGROUND: Deletions of the imprinting centre 1 (IC1) in 11p15.5 are rare and their clinical significance is not only influenced by their parental origin but also by their exact genomic localization. In case the maternal IC1 allele is affected, the deletion is associated with the overgrowth disorde...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Clin Epigenetics
Hauptverfasser: Kraft, Florian, Wesseler, Katharina, Begemann, Matthias, Kurth, Ingo, Elbracht, Miriam, Eggermann, Thomas
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6377752/
https://ncbi.nlm.nih.gov/pubmed/30770769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-019-0629-x
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