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A Drosophila model of the rhabdomyosarcoma initiator PAX7-FKHR
Alveolar rhabdomyosarcoma (ARMS) is an aggressive myogenic-type tumor and a gain-of-function disease, caused by misexpression of the PAX3-FKHR or PAX7-FKHR fusion oncoprotein from structurally rearranged chromosomes. PAX3-FKHR misexpressed in terminally differentiating mouse myofibers can cause rhab...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2006
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1569182/ https://ncbi.nlm.nih.gov/pubmed/16938866 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0605926103 |
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