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PAX3-FKHR regulates the expression of pleiotrophin to mediate motility in alveolar rhabdomyosarcoma cells

More than 80% of the aggressive alveolar rhabdomyosarcoma (ARMSs) harbor a PAX3-FKHR fusion transcription factor, which regulates cell motility and promotes metastasis. Our hypothesis is that PAX3-FKHR regulates cell motility by regulating the expression of its transcriptional targets that are also...

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Autores principales: Liu, Lingling, Chen, Taosheng
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3859525/
https://ncbi.nlm.nih.gov/pubmed/24348888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6000/1929-2279.2012.01.01.09
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