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Selective utilization of nonhomologous end-joining and homologous recombination DNA repair pathways during nervous system development
The repair of DNA double-strand breaks (DSBs) occurs via nonhomologous end-joining (NHEJ) or homologous recombination (HR). These mechanistically distinct pathways are critical for maintenance of genomic integrity and organismal survival. Although inactivation of either pathway leads to embryonic le...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1502498/ https://ncbi.nlm.nih.gov/pubmed/16777961 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0602436103 |
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