DNA Repair by Homologous Recombination, But Not by Nonhomologous End Joining, Is Elevated in Breast Cancer Cells

Aberrant double-stranded break (DSB) repair leads to genomic instability, which is a hallmark of malignant cells. Double-stranded breaks are repaired by two pathways: homologous recombination (HR) and nonhomologous DNA end joining (NHEJ). It is not known whether these repair pathways are affected in...

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Bibliographic Details
Main Authors: Mao, Zhiyong, Jiang, Ying, Liu, Xiang, Seluanov, Andrei, Gorbunova, Vera
Format: Artigo
Language:Inglês
Published: Neoplasia Press Inc. 2009
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2697354/
https://ncbi.nlm.nih.gov/pubmed/19568413
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