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DNA repair by nonhomologous end joining and homologous recombination during cell cycle in human cells

DNA double-strand breaks (DSBs) are dangerous lesions that can lead to potentially oncogenic genomic rearrangements or cell death. The two major pathways for repair of DSBs are nonhomologous end joining (NHEJ) and homologous recombination (HR). NHEJ is an intrinsically error-prone pathway while HR r...

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Библиографические подробности
Главные авторы: Mao, Zhiyong, Bozzella, Michael, Seluanov, Andrei, Gorbunova, Vera
Формат: Artigo
Язык:Inglês
Опубликовано: 2008
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754209/
https://ncbi.nlm.nih.gov/pubmed/18769152
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