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DNA repair by nonhomologous end joining and homologous recombination during cell cycle in human cells

DNA double-strand breaks (DSBs) are dangerous lesions that can lead to potentially oncogenic genomic rearrangements or cell death. The two major pathways for repair of DSBs are nonhomologous end joining (NHEJ) and homologous recombination (HR). NHEJ is an intrinsically error-prone pathway while HR r...

詳細記述

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書誌詳細
主要な著者: Mao, Zhiyong, Bozzella, Michael, Seluanov, Andrei, Gorbunova, Vera
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754209/
https://ncbi.nlm.nih.gov/pubmed/18769152
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