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TRF2 is required for repair of nontelomeric DNA double-strand breaks by homologous recombination
TRF2 (telomeric repeat binding factor 2) is an essential component of the telomeric cap, where it forms and stabilizes the T-loop junctions. TRF2 forms the T-loops by stimulating strand invasion of the 3′ overhang into duplex DNA. TRF2 also has been shown to localize to nontelomeric DNA double-stran...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1941808/ https://ncbi.nlm.nih.gov/pubmed/17670947 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0702410104 |
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