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Analysis of DNA Double-strand Break (DSB) Repair in Mammalian Cells

DNA double-strand breaks are the most dangerous DNA lesions that may lead to massive loss of genetic information and cell death. Cells repair DSBs using two major pathways: nonhomologous end joining (NHEJ) and homologous recombination (HR). Perturbations of NHEJ and HR are often associated with prem...

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Detalhes bibliográficos
Main Authors: Seluanov, Andrei, Mao, Zhiyong, Gorbunova, Vera
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157866/
https://ncbi.nlm.nih.gov/pubmed/20864925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/2002
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