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Analysis of DNA Double-strand Break (DSB) Repair in Mammalian Cells
DNA double-strand breaks are the most dangerous DNA lesions that may lead to massive loss of genetic information and cell death. Cells repair DSBs using two major pathways: nonhomologous end joining (NHEJ) and homologous recombination (HR). Perturbations of NHEJ and HR are often associated with prem...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
MyJove Corporation
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3157866/ https://ncbi.nlm.nih.gov/pubmed/20864925 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/2002 |
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