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TRF2 is required for repair of nontelomeric DNA double-strand breaks by homologous recombination

TRF2 (telomeric repeat binding factor 2) is an essential component of the telomeric cap, where it forms and stabilizes the T-loop junctions. TRF2 forms the T-loops by stimulating strand invasion of the 3′ overhang into duplex DNA. TRF2 also has been shown to localize to nontelomeric DNA double-stran...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mao, Zhiyong, Seluanov, Andrei, Jiang, Ying, Gorbunova, Vera
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1941808/
https://ncbi.nlm.nih.gov/pubmed/17670947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0702410104
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