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Comparison of nonhomologous end joining and homologous recombination in human cells
The two major pathways for repair of DNA double-strand breaks (DSBs) are homologous recombination (HR) and nonhomologous end joining (NHEJ). HR leads to accurate repair, while NHEJ is intrinsically mutagenic. To understand human somatic mutation it is essential to know the relationship between these...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2695993/ https://ncbi.nlm.nih.gov/pubmed/18675941 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2008.06.018 |
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