Measuring nonhomologous end-joining, homologous recombination and alternative end-joining simultaneously at an endogenous locus in any transfectable human cell

Double strand break (DSB) repair primarily occurs through 3 pathways: non-homologous end-joining (NHEJ), alternative end-joining (Alt-EJ), and homologous recombination (HR). Typical methods to measure pathway usage include integrated cassette reporter assays or visualization of DNA damage induced nu...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Hussain, Suleman S, Majumdar, Rahul, Moore, Grace M, Narang, Himanshi, Buechelmaier, Erika S, Bazil, Maximilian J, Ravindran, Pavithran T, Leeman, Jonathan E, Li, Yi, Jalan, Manisha, Anderson, Kyrie S, Farina, Andrea, Soni, Rekha, Mohibullah, Neeman, Hamzic, Edin, Rong-Mullins, Xiaoqing, Sifuentes, Christopher, Damerla, Rama R, Viale, Agnes, Powell, Simon N, Higginson, Daniel S
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2021
Fag:
Methods Online
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8287935/
https://ncbi.nlm.nih.gov/pubmed/33877327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab262
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