Measuring nonhomologous end-joining, homologous recombination and alternative end-joining simultaneously at an endogenous locus in any transfectable human cell

Double strand break (DSB) repair primarily occurs through 3 pathways: non-homologous end-joining (NHEJ), alternative end-joining (Alt-EJ), and homologous recombination (HR). Typical methods to measure pathway usage include integrated cassette reporter assays or visualization of DNA damage induced nu...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Hussain, Suleman S, Majumdar, Rahul, Moore, Grace M, Narang, Himanshi, Buechelmaier, Erika S, Bazil, Maximilian J, Ravindran, Pavithran T, Leeman, Jonathan E, Li, Yi, Jalan, Manisha, Anderson, Kyrie S, Farina, Andrea, Soni, Rekha, Mohibullah, Neeman, Hamzic, Edin, Rong-Mullins, Xiaoqing, Sifuentes, Christopher, Damerla, Rama R, Viale, Agnes, Powell, Simon N, Higginson, Daniel S
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Methods Online
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8287935/
https://ncbi.nlm.nih.gov/pubmed/33877327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab262
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