Measuring nonhomologous end-joining, homologous recombination and alternative end-joining simultaneously at an endogenous locus in any transfectable human cell

Double strand break (DSB) repair primarily occurs through 3 pathways: non-homologous end-joining (NHEJ), alternative end-joining (Alt-EJ), and homologous recombination (HR). Typical methods to measure pathway usage include integrated cassette reporter assays or visualization of DNA damage induced nu...

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Bibliografski detalji
Izdano u:Nucleic Acids Res
Glavni autori: Hussain, Suleman S, Majumdar, Rahul, Moore, Grace M, Narang, Himanshi, Buechelmaier, Erika S, Bazil, Maximilian J, Ravindran, Pavithran T, Leeman, Jonathan E, Li, Yi, Jalan, Manisha, Anderson, Kyrie S, Farina, Andrea, Soni, Rekha, Mohibullah, Neeman, Hamzic, Edin, Rong-Mullins, Xiaoqing, Sifuentes, Christopher, Damerla, Rama R, Viale, Agnes, Powell, Simon N, Higginson, Daniel S
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2021
Teme:
Methods Online
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8287935/
https://ncbi.nlm.nih.gov/pubmed/33877327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab262
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