Measuring nonhomologous end-joining, homologous recombination and alternative end-joining simultaneously at an endogenous locus in any transfectable human cell

Double strand break (DSB) repair primarily occurs through 3 pathways: non-homologous end-joining (NHEJ), alternative end-joining (Alt-EJ), and homologous recombination (HR). Typical methods to measure pathway usage include integrated cassette reporter assays or visualization of DNA damage induced nu...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Nucleic Acids Res
मुख्य लेखकों: Hussain, Suleman S, Majumdar, Rahul, Moore, Grace M, Narang, Himanshi, Buechelmaier, Erika S, Bazil, Maximilian J, Ravindran, Pavithran T, Leeman, Jonathan E, Li, Yi, Jalan, Manisha, Anderson, Kyrie S, Farina, Andrea, Soni, Rekha, Mohibullah, Neeman, Hamzic, Edin, Rong-Mullins, Xiaoqing, Sifuentes, Christopher, Damerla, Rama R, Viale, Agnes, Powell, Simon N, Higginson, Daniel S
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Oxford University Press 2021
विषय:
Methods Online
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC8287935/
https://ncbi.nlm.nih.gov/pubmed/33877327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab262
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